Active research groups

 | تاریخ ارسال: ۱۳۹۶/۷/۴ | 

Active Research Groups

 
1. Department of Anatomical Sciences, Tehran University of Medical Sciences & Institute of Neuroanatomy, RWTH Aachen University
                                    
 
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                               Prof. Iraj Ragerdi   Kashani   (CV)                                                     Prof. Cordian Beyer (CV)                                                                        

                                                                                                                                                        

 
 Research interests  :
•   Amyotrophic lateral sclerosis (ALS) 
•   Eating disorders/Anorexia nervosa (AN) 
•   Multiple sclerosis (MS) 
•   Oxidative stress 
•   Spinal cord injury 
•   Stroke and ischemia
•   Regenerative Medicine  
•   Cell Therapy

Publications:
  • Reprod Toxicol. 2017 Aug 14. pii: S0890-6238(17)30101-6. doi: 10.1016/j.reprotox.2017.08.006.
Role of stromal derived factor-1a (SDF-1a) for spermatogenesis of busulfan-injured rats.
Khanlarkhani N, Mortezaee K, Amidi F, Kharazinejad , Beyer C, Baazm M, Pasbakhsh P, Pazhohan A, Sobhani A, Zendedel A.
  • Int Immunopharmacol. 2017 Aug 19;51:131-139. doi: 10.1016/j.intimp.2017.08.007.
Progesterone therapy induces an M1 to M2 switch in microglia phenotype and suppresses NLRP3 inflammasome in a cuprizone-induced demyelination mouse model.
Aryanpour R, Pasbakhsh P, Zibara K, Namjoo Z, Beigi Boroujeni F, Shahbeigi S, Kashani IR, Beyer C, Zendehdel A.
  • Mol Neurobiol. 2017 Jan 27. doi: 10.1007/s12035-017-0400-2.
Estrogen Attenuates Local Inflammasome Expression and Activation after Spinal Cord Injury.
Zendedel A, Mönnink F, Hassanzadeh G, Zaminy A, Ansar MM, Habib P, Slowik A, Kipp M, Beyer C.
  • Molecular Neurobiology , July 2016, Volume 53, Issue 5, pp 3063–3075
Activation and Regulation of NLRP3 Inflammasome by Intrathecal Application of SDF-1a in a Spinal Cord Injury Model
Adib Zendedel ,Sonja Johann, Soraya Mehrabi, Mohammad-taghi Joghataei , Gholamreza Hassanzadeh, Markus Kipp, Cordian Beyer
  • Metabolic Brain Disease, April 2016, Volume 31, Issue 2, pp 425–433
Regulatory effect of triiodothyronine on brain myelination and astrogliosis after cuprizone-induced demyelination in mice
Adib Zendede, Iraj Ragerdi Kashani, Maryam Azimzadeh, Parichehr Pasbakhsh, Negar Omidi, Abolfazl Golestani, Cordian Beyer, Tim Clarner
 
2. Genetics Research Center, University of Social Welfare and Rehabilitation Sciences & Max-Planck Institute for Molecular Genetics
 
                     
          Prof. Hossein Najmabadi  (CV)                                                          Prof. Hans Hilger Ropers  (CV)                                      

                                                                                                                                       

    
  
  
 
 Research interests  :
•   Genetic diagnosis of intellectual disability (ID)
•   Autosomal recessive cognitive defects
•   Molecular causes of mental retardation
•   Genetic diagnosis of Neuromuscular Disorders


Publications:
  • Am J Hum Genet. 2017 Aug 12. pii: S0002-9297(17)30288-4. doi: 10.1016/j.ajhg.2017.07.010.
Homozygous Truncating Variants in TBC1D23 Cause Pontocerebellar Hypoplasia and Alter Cortical Development.
Ivanova EL, Mau-Them FT, Riazuddin S, Kahrizi K, Laugel V, Schaefer E, de Saint Martin A, Runge K1, Iqbal Z, Spitz MA, Laura M, Drouot N, Gérard B, Deleuze JF1, de Brouwer APM, Razzaq A, Dollfus H, Assir MZ, Nitchké P, Hinckelmann MV, Ropers H, Riazuddin S, Najmabadi H, van Bokhoven H, Chelly J.
  • Hum Mutat. 2017 Jun;38(6):621-636. doi: 10.1002/humu.23205. Epub 2017 Mar 23.
Mutations of the aminoacyl-tRNA-synthetases SARS and WARS2 are implicated in the etiology of autosomal recessive intellectual disability.
Musante L, Püttmann L, Kahrizi K, Garshasbi M, Hu H1, Stehr H, Lipkowitz B, Otto S, Jensen LR, Tzschach A, Jamali P, Wienker T, Najmabadi H, Ropers HH, Kuss AW
  • Hum Mutat. 2017 Jun;38(6):621-636. doi: 10.1002/humu.23205. Epub 2017 Mar 23.
Mutations of the aminoacyl-tRNA-synthetases SARS and WARS2 are implicated in the etiology of autosomal recessive intellectual disability.
Musante L1, Püttmann L1, Kahrizi K2, Garshasbi M1, Hu H1, Stehr H3, Lipkowitz B1, Otto S1, Jensen LR4, Tzschach A1, Jamali P5, Wienker T1, Najmabadi H2, Ropers HH1, Kuss AW4.
  • PLoS Genet. 2016 May 11;12(5):e1006022. doi: 10.1371/journal.pgen.1006022. eCollection 2016 May.
BOD1 Is Required for Cognitive Function in Humans and Drosophila.
Esmaeeli-Nieh S, Fenckova M, Porter IM, Motazacker MM, Nijhof B, Castells-Nobau A, Asztalos Z, Weißmann R, Behjati F, Tzschach A, Felbor U, Scherthan H, Sayfati SM, Ropers HH, Kahrizi K, Najmabadi H, Swedlow JR, Schenck A, Kuss AW.
  • PLoS One. 2015 Aug 26;10(8):e0129631. doi: 10.1371/journal.pone.0129631. eCollection 2015.
The Role of a Novel TRMT1 Gene Mutation and Rare GRM1 Gene Defect in Intellectual Disability in Two Azeri Families.
Davarniya B, Hu H, Kahrizi K, Musante L, Fattahi Z, Hosseini M, Maqsoud F, Farajollahi R, Wienker TF, Ropers HH, Najmabadi H


 
3. Department of Neuroscience, Mashhad University of Medical Sciences & Department of Neurosurgery, Westfälische Wilhelms-Universität Münster



                     Prof. Ali Gorji  (CV)                                                                                    Prof. Walter Stummer (CV)
                                                                                                                                 


 Research interests  :
  • pathophysiological mechanisms of epilepsy
  • cellular and slice electrophysiology 
  • Spreading depression and its role in different neurological disorders 
Publications:
  • Cephalalgia. 2017 Jan 1:333102417702132. doi: 10.1177/0333102417702132.
Astrocyte-mediated inflammation in cortical spreading depression.
Ghaemi A, Alizadeh L, Babaei S, Jafarian M, Khaleghi Ghadiri M, Meuth SG, Kovac S, Gorji A
  • Mol Neurobiol. 2017 Jun 13. doi: 10.1007/s12035-017-0642-z.
Apoptosis Following Cortical Spreading Depression in Juvenile Rats.
Jahanbazi Jahan-Abad A, Alizadeh L, Sahab Negah S, Barati P, Khaleghi Ghadiri M, Meuth SG, Kovac S, Gorji A
  • Trends Pharmacol Sci. 2016 Jul;37(7):511-21. doi: 10.1016/j.tips.2016.04.004. Epub 2016 May 5.
Tightrope or Slackline? The Neuroscience of Psychoactive Substances.
Coulon P, Gorji A.
  • Brain Struct Funct. 2017 Aug;222(6):2773-2785. doi: 10.1007/s00429-017-1371-9. Epub 2017 Feb 16.
Developmental changes in Notch1 and NLE1 expression in a genetic model of absence epilepsy.
Karimzadeh F, Modarres Mousavi SM, Alipour F, Hosseini Ravandi H, Kovac S3, Gorji A.
  • Mol Neurobiol. 2016 Sep;53(7):4675-84. doi: 10.1007/s12035-015-9404-y. Epub 2015 Aug 27.
The Effect of Melatonin on Behavioral, Molecular, and Histopathological Changes in Cuprizone Model of Demyelination.
Vakilzadeh G, Khodagholi F, Ghadiri T, Ghaemi A, Noorbakhsh F, Sharifzadeh M, Gorji A


 

 


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